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- NADPH oxidase - Wikipedia
NADPH oxidase catalyzes the production of a superoxide free radical by transferring one electron to oxygen from NADPH [ 2 ] NADPH + 2O 2 ⇌ NADP + + 2O − 2 + H +
- NADPH Oxidases (NOX): An Overview from Discovery, Molecular . . .
NOX from phagocytes catalyzes, via one-electron trans-membrane transfer to molecular oxygen, the production of the superoxide anion Over the years, six human homologs of the catalytic subunit of the phagocyte NADPH oxidase were found: NOX1, NOX3, NOX4, NOX5, DUOX1, and DUOX2
- NADPH Oxidases: Functions and Pathologies in the Vasculature
These enzymes transfer electrons from NADPH to molecular oxygen, thus producing superoxide (O 2 ·−) Because O 2 ·− does not readily cross membranes and is short-lived, its effect is mostly local
- NADPH—The Forgotten Reducing Equivalent - PMC
NADPH oxidases (NOXs) produce ROS The NOX family of proteins localizes to the plasma, endoplasmic reticulum, and mitochondrial membranes NOX catalytic subunits transfer electrons from NADPH across the membranes to molecular oxygen to generate O 2 − superoxide or H 2 O 2 hydrogen peroxide
- NADPH Oxidase - an overview | ScienceDirect Topics
NADPH oxidase produces O 2 − by transferring electrons from NADPH inside the cell across the cell membrane and reducing molecular oxygen Several isoforms of NADPH oxidase (Nox) are found expressed in various cell types of the vascular wall, including endothelial cells, smooth muscle cells, and fibroblasts [2]
- NADPH Oxidases: Functions and Pathologies in the Vasculature
These enzymes transfer electrons from NADPH to molecular oxygen producing superoxide (O 2 •−) Because O 2 •− does not readily cross membranes and is short-lived, its effect is mostly local
- Reactive Oxygen Species Flashcards - Quizlet
This catalyzes the transfer of electrons from NADPH to oxygen, resulting in the formation of superoxide in the extracellular compartment (phagolysosome) Subsequent reactions via SOD, catalase, or myeloperoxidase (MPO), occurring in the phagolysosome, can result in the formation of H2O2, H2O, or HOCl-, respectively
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