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Canada-205970-INDEPENDENT SCHOOL selskapets Kataloger
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Firma Nyheter:
- Retinoid X Receptor: Cellular and Biochemical Roles of . . . - Springer
Retinoid X receptors (RXRs) present a subgroup of the nuclear receptor superfamily with particularly high evolutionary conservation of ligand binding domain The receptor exists in α, β, and γ isotypes that form homo- heterodimeric complexes with other permissive and non-permissive receptors
- Retinoid X receptor - Wikipedia
There are three retinoic X receptors (RXR): RXR-alpha, RXR-beta, and RXR-gamma, encoded by the RXRA, RXRB, RXRG genes, respectively RXR heterodimerizes with multiple nuclear receptors including CAR, FXR, LXR, PPAR, [6] PXR, RAR, TR, ER and VDR
- The PPAR-RXR Transcriptional Complex in the Vasculature:
New insights into fundamental aspects of PPAR and RXR biology, and their actions in the vasculature, continue to appear Although RXRs are obligate heterodimeric partners for PPAR action, the part that RXRs, and their endogenous retinoid mediators, exert in the vessel wall is less well understood
- RARα RXR Synergism Potentiates Retinoid Responsiveness in Cutaneous T . . .
Retinoids, natural and synthetic derivatives of vitamin A, induce cellular changes by activating nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR)
- The Retinoid X Receptors and Their Ligands - PMC
LXRα (NR1H3) DR-4: Predominant in adipose tissue, adrenal gland, intestine, kidney, liver (highest), macrophage, and spleen Oxysterols such as 22R-OH-cholesterol [37,58,87,88,136,184]Cholesterol homeostasis by cholesterol transport and catabolism and triacyl glycerol synthesis gene regulation (induces ATP-binding cassette transporters (ABCA1) for efflux of cholesterol and phospholipids from
- The retinoid X receptor and its ligands: versatile regulators of . . .
Retinoid X Receptors (RXRs) consist of a family of nuclear receptors that target and regulate multiple signalling pathways The early evolutionary emergence of RXRs in comparison to other nuclear receptors may have allowed for the development of unique properties as transcriptional regulators
- Research Resource: Transcriptome Profiling of Genes Regulated by RXR . . .
Abstract Retinoid X receptors (RXRs) are heterodimerization partners for many nuclear receptors and also act as homodimers Heterodimers formed by RXR and a nonpermissive partner, e g retinoic acid receptor (RAR) and vitamin D receptor (VDR), can be activated only by the agonist of the partner receptor In contrast, heterodimers that contain permissive partners, e g liver X receptor (LXR
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