Statin Intolerance Pathway - NHS England • Intolerance to initial statin therapy is defined by NICE as the presence of clinically significant adverse effects that represent an unacceptable risk to the patient or that may reduce compliance with therapy
NHS England statin intolerance pathway - NICE This guideline covers identifying and assessing risk of cardiovascular disease (CVD) in adults without established CVD It covers lifestyle changes and lipid-lowering treatment (including statins) for primary and secondary prevention of CVD, and includes guidance for people who also have diabetes or chronic kidney disease
Statin Intolerance Pathway This pathway should only be used for patients with confirmed statin intolerance, defined as the inability to tolerate at least two different statins, including at least one at the lowest approved dose after all appropriate rechallenge strategies have been attempted
Lipid Management – BLMKICB Medicines Optimisation In addition, the following treatment summaries have been developed by the Accelerated Access Collaborative (AAC) and endorsed by NICE, which include information on Lipid Management in Primary Prevention and Managing Statin Intolerance
Scenario: Secondary prevention of CVD | Management - CKS | NICE The AAC Statin Intolerance Pathway provides useful information on managing potential statin intolerance, including alternate-day or twice-weekly dosing regimens for people who cannot tolerate statins daily
Statin intolerance - GPnotebook seek specialist advice about options for treating people at high risk of CVD such as those with CKD, type 1 diabetes, type 2 diabetes or genetic dyslipidaemias, and those with CVD, who are intolerant to 3 different statins Advice can be sought for example, by telephone, virtual clinic or referral See linked management algorithm 1
North Yorkshire and York Lipid Treatment Guidance • If statin is not tolerated, follow statin intolerance pathway and consider alternative lipid lowering medicines such as ezetimibe etc in line with the treatment pathway
Medication: Statin Intolerance Pathway - Medscape UK This pathway brings together multiple NICE clinical guidelines (CGs) and technology appraisals (TAs) into a single document, to support a consistent approach to the management of statin intolerance The guidelines and TAs included are: CG71: Familial hypercholesterolaemia: identification and management
Guidelines | Tackling Cholesterol Together - HEART UK This area provides pathway resources such as Statin intolerance and Lipid management Check out our interactive Lipid management pathway; which is an interactive version of the AAC, NICE-endorsed Summary of National Guidance for Lipid Management for Primary and Secondary Prevention of CVD