What are the side effects of vaping? - Drugs. com Vaping involves inhaling and exhaling the vapor produced by an e-cigarette (EC) or similar device (such as a vape pen or MOD) The most common side effects of vaping include: Addiction to nicotine (unless nicotine-free cartridges are used) Coughing Dehydration Dizziness Dry nose Eye irritation Exacerbation of asthma in people, with pre-existing asthma Headaches Nausea Sensitive teeth A sore