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- Familial Isolated Hypoparathyroidism - Symptoms, Causes . . .
Familial isolated hypoparathyroidism is caused by changes (mutations) in one of several different genes 1-4 The first symptoms usually appear in infancy, childhood, or young adulthood The most common cause of hypoparathyroidism in adults is damage to or removal of the parathyroid glands due to neck surgery View Full Report Show Less
- Genetic disorders of parathyroid development and function
Genetic defects account for disorders of parathyroid gland formation, dysregulation of parathyroid hormone synthesis or secretion, and autoimmune destruction of the parathyroid glands Genetic hypoparathyroidism may be sporadic or exhibit autosomal dominant, autosomal recessive, or X-linked recessive inheritance Acknowledgments:
- Hypoparathyroidism: Symptoms Treatment - Cleveland Clinic
Both adults and children can get hypoparathyroidism Adults are more likely to get hypoparathyroidism from accidental damage to their parathyroid glands during surgery Children are more likely to have hypoparathyroidism due to a genetic condition Complications of hypoparathyroidism Long-term complications of hypoparathyroidism can include:
- Hypoparathyroidism - Symptoms causes - Mayo Clinic
If you've had surgery or radiation involving your thyroid or neck, be aware of possible hypoparathyroidism symptoms These can include a tingling or burning feeling in the fingers, toes or lips, or muscle twitching or cramping If you get symptoms, your healthcare professional might recommend prompt treatment with calcium and vitamin D
- Hypoparathyroidism - StatPearls - NCBI Bookshelf
Under physiologic circumstances, calcium concentration in the extracellular fluid is maintained within a narrow range [1] Normal calcium homeostasis depends on a complex set of hormonal regulatory mechanisms that include the effects of parathyroid hormone (PTH), vitamin D metabolites, and calcitonin on calcium transport in bone, kidneys, and the gastrointestinal tract [2][3] Hypoparathyroidism
- Hypoparathyroidism - Nature Reviews Disease Primers
Hypoparathyroidism has a genetic aetiology in <10% of cases 3 However, chromosomal microdeletions and monogenic abnormalities represent the major cause of hypoparathyroidism in children 30
- Types Causes of HypoPARAthyroidism
Non-Surgical HypoPARAthyroidism Genetic HypoPARAthyroidism Symptoms of genetic hypoPARA present in the first few years of life, absent surgical causes There is often a family history of the condition Genetic hypoPARA may be part of a syndrome involving other organs or tissues, such as: DiGeorge Syndrome; Kenny-Caffey Syndrome
- Hypoparathyroidism: Genetics and Diagnosis - PubMed
This narrative report summarizes diagnostic criteria for hypoparathyroidism and describes the clinical presentation and underlying genetic causes of the nonsurgical forms We conducted a comprehensive literature search from January 2000 to January 2021 and included landmark articles before 2000, pre …
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